• Wendy Finkelstein

Mitochondrial Insight: Where is your Energy Going?

Mitochondrial medicine is at the heart of most DIS-ease, and is also the gateway to Regenerative Healthand Longevity

Every cell in our body except red blood cells has mitochondria.The total weight of your mitochondria is similar to that of a sim card in your phone. It is your BATTERY. It holds your voltage and without healthy mitochondria, accelerated “INFLAMMAGING” will occur.

Mitochondria are where we make energy known as ATP. In order to make energy we must have oxygen. Oxygen increases our voltage and travels through our bodies water to ultimately serve the mitochondria in our tissues. Oxygen and water together form an electromagnetic symphony that encourages life to exist. Having mitochondria is essential to life and is the reason why we breathe.

As we age our toxin burden increases and the energy we make creates more free radicals. Your environment can radically affect the health of your mitochondria. Things such as eating an ultra-processed, high gluten, dairy, and sugar diet, exposure to harmful toxins, heavy metals, low grade infection, gum disease, diabetes, obesity and thyroid imbalances all impair mitochondrial resiliency.

Once mitochondrial reserve is depleted, symptoms including exhaustion, muscle aches, brain fog, memory loss, pain and stiffness rise. Unfortuntely we have been programmed to agree that most of the signs that we typically think of as “normal aging” aren’t actually normal, and they can be traced back to the function of your mitochondria.

Energetically speaking, mitochondrial degeneration equates to states of LOW OXYGEN =LOW pH= LOW ENERGY =INFLAMMATION. The body needs power/voltage to exist let alone initiate a healing process.

Mitochondria carry maternal DNA and are involved in the transcription and repair of our cells. Mitochondrial decay causes poor gene transcription (cancer) as well as loss of vitality (energy).

Below are a glossary of terms used in the literature to describe the cellular physiology of mitochondria and their role in lifespan, DIS-ease, and regenenerative health:

Telomeres: Telomeres are end caps on your chromosomes Like the plastic shells on the tips of shoelaces. Telomeres help protect your DNA and unfortunately, naturally decrease with age. However, there are known environmental triggers that cause them to shorten or lengthen, which is important because telomere length is associated with lifespan.

Sirtuins: Sirtuins are a class of enzymes that act on your insulin production pathway. They’ve also been found to support brain health, cognition, and even muscle function. They are also important for keeping your liver healthy and protecting against reactive oxygen species (ROS) known to cause cellular damage.

Senescent cells: Senescent cells are otherwise known as zombie cells. Normally, as cells age or become non-functional, the mitochondria sends messages to the nucleus to initiate cell death. This is called, apoptosis. Senescent cells, however don’t get a clear message due to mitochondrial weakness and instead don’t fully die or clear off. Instead, they leak massive amounts of inflammatory compounds and can infect nearby cells. Senescent cells accumulate with age, but can accumulate quicker in those with a poor mitochondrial function

AMP-Activated Protein Kinase (AMPK): AMPK is an enzyme found in many of your tissues and is activated during times of “good” stress (called hormesis). When AMPK is activated, it exhibits many protective and beneficial effects, like protecting against insulin resistance, inflammation, fat storage, and mitochondrial dysfunction.

Mammalian/Mechanistic Target of Rapamycin (MTOR): When the MTOR pathway is activated, it can cause abnormal cell growth, unfavorable protein synthesis, disrupted mitochondrial function, and can cause increased accumulation of senescent cells. Much of longevity research focuses on how to inhibit the activation of MTOR as a way to increase lifespan. Intermittent fasting is one such way to decreasee MTOR.

All of these longevity enzymes and pathways have one thing in common: they are all intimately interdependent on your mitochondria.

So, what’s the best way to support those life-giving organelles to influence all of the longevity pathways?

1. Eat Real Food. Fill your plate with non-starchy veggies, add a small portion of quality protein (i.e. grass-fed, pasture-raised, organic), include a serving or two of healthy fats, and try to eat foods the way they look in nature. Always ask: did nature make this, or did man? If nature made it: eat! If man made it: skip.

2. Move Your Body. Exercise doesn’t have to be a three-hour session at the gym. Any type of movement is good for your body. So, if joining a gym is not your thing, try a different hobby: start a garden, play a sport, go for a hike, go for a swim, play with your kids or grandkids, take a dance class, etc. Enjoying the benefits of exercise comes in all forms.

3. Get Good Sleep. Sleep must be a priority. It is the only way to repair. Our society, social media and screen time has made quality sleep very difficult: Below are some tips to help re-establish good sleep hygiene.

Turn off electronics an hour before bed (they disrupt your circadian rhythm). Wear blue light glasses when on screen to preserve melatonin.

Wake up and go to sleep at the same times every day (this enhances your circadian rhythm).

Step outside right when the sun rises (this also enhances your circadian rhythm). Direct sunshine first thing in the morning activates vitamin D, boosts mood and re-connects us to the powers of the planet.

Leave at least 2 hours between your last meal or snack and bedtime.

Keep your room cool, remove hot blankets and crank the ac.

There’s a lot you can do to support the health of your mitochondria. Nephesh offers the full spectrum of mitochondria testing and mitiochondrial rescue supplement protocols.

Testing and services includes lifespan analysis, epigenetics, metabolic performance panels that look directly at energy production, heart rate variability testing, hyperbaric oxygen therapy, heavy metal testing and much more. Stay tuned for upcoming packages.

Remember your Nephesh is activated through your throat and its ability to vibrate, So sing, express laugh and BE YOU!!

In love and Service,

Wendy Finkelstein

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